Background Metabotropic glutamate receptor 3 (mGlu3, mGluR3), encoded by GRM3, is normally a risk gene for schizophrenia and a therapeutic target. comparison subjects, genotyped for GRM3 SNP rs10234440. Results One (out of six) anti-mGlu3 antibodies was fully validated, a C-terminal antibody which detected monomeric (~?100?kDa) and dimeric (~?200?kDa) mGlu3. A second, N-terminal, antibody detected the… Continue reading Background Metabotropic glutamate receptor 3 (mGlu3, mGluR3), encoded by GRM3, is