Background MXD3 is a basic-helix-loop-helix-leucine-zipper transcription factor involved in cellular proliferation. and gene ontology analysis we identify several major pathways enriched in response to acute (immune response, apoptosis, cell cycle) versus persistent (cell adhesion) MXD3 activation. Conclusions In this study, we demonstrate that acute MXD3 activation results in a transient increase in cell proliferation while… Continue reading Background MXD3 is a basic-helix-loop-helix-leucine-zipper transcription factor involved in cellular proliferation.